"Failed to CoCreate profiler" in log after uninstalling ANTS
I'd say it's more than likely that it has something to do with the profiler core component. This should only be called, however, if ANTS Profiler has enabled profiling for the application.
If the last thing that you had profiled was a web service or web application, can you try stopping and starting IISADMIN using the IISRESET command from the console?
Otherwise, I think it could be that ANTS Profiler has somehow interfered with another vendor's profiler (such as DevPartner's), so it might help to uninstall and reinstall their software.